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Tools & Techniques Cancer

The Story and Science Behind the "Mini-brain"

| Simon Plummer

How iPSC-derived 3D organoids and high-throughput histology opens a new door to personalized medicine development and testing.

Research Field Gene Editing

It's CRISPR Crunch Time

| Jonathan James

China drafts new gene-editing regulations – but concerns over their enforcement remain.

Research Field Cell & gene therapy

Now For the High-Hanging Fruit

| Miguel Forte

We should be thrilled with the success of the approved CD-19 CAR-T therapies. But the field is still young, and we are only scratching the surface of what’s possible.

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Latest Articles

Disease Area Metabolism & Diabetes

Bite-size Breakthroughs: IELS, Imaging and Ocular Cancer

| Jonathan James

The latest advances in translational medicine – condensed into 20-second servings.

Disease Area Cancer

Gurus of Brain Oncology

| Jonathan James

Three leading lights in the neuro-oncology sphere explain what inspired them, how the field has evolved, and what challenges lie ahead.

Disease Area Cancer

Adaptive Invaders

| Jonathan James

New evidence suggests there’s more to metastasis than MMPs, demanding a therapeutic rethink.

Disease Area Metabolism & Diabetes

Grappling GK

| Jonathan James

How a new compound promises to selectively activate hepatic glucokinase in a bid to treat type 2 diabetes.

Research Field Drug discovery

The Centryin of Attention

| Jonathan James

A novel protein platform helps neutralize powerful MRSA toxins.

Disease Area Neurological

Breakdown Breakthrough

| Jonathan James

Exploring the link between blood brain barrier permeability and cognitive dysfunction.

Tools & Techniques Informatics

RePURPOSED

| Maryam Mahdi

Recycled and reused: scientists develop a library to help teach old drugs new tricks.

Disease Area Neurological

The Fear of Fat

| Jonathan James

Obesity-induced anxiety might be caused by the accumulation of fatty senescent glial cells – and cleared by senolytics.

Disease Area Cancer

Load Versus Response

| Jonathan James

Higher tumor mutational burden is linked to improved survival across multiple cancer types.

Disease Area Neurological

Alzheimer's Awakening

| Jonathan James

Changes in non-REM sleep may indicate early AD

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