Disease Area Neurological

Getting on Target for Alzheimer’s

01/03/2020 | Neil Cashman, James Kupiec

Biogen’s aducanumab reversal not only puts hope on the horizon for a near-term Alzheimer’s treatment, it also revitalizes work supporting next-generation amyloid beta (Aß)-targeting candidates.

Tools & Techniques Clinical trials

A Framework for Translation

12/09/2019 | Jonathan James

Andrew Davies, Professor of Haematological Oncology and Consultant Medical Oncologist at the University of Southampton, and Nigel Blackburn, Cancer Research UK’s Director of Drug Development, discuss a partnership that focuses on early-phase clinical trials

Research Field Neuroscience

A Better AD Model

07/29/2019 | Brett Spangler

How primary neuronal cell cultures are unraveling the role of amyloid β oligomers in Alzheimer’s disease.

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Latest Articles

Tools & Techniques Diagnostics & prognostics

All the RAGE

09/24/2019 | Luke Turner

A new genomic barcode tracker could help spot the rare immune cells that are most effective against cancer

Research Field Pain & critical care

An Osteoarthritic Odyssey

07/23/2019

Sitting Down With… Mike Clayman, CEO of Flexion Therapeutics, Inc., Burlington, Massachusetts, USA.

Research Field Cell & molecular biology

In the RNA

07/12/2019 | Stephanie Sutton

RNA Inhibitors - an exciting avenue for drug development? We collate the findings from the Innovation that Matters series, hosted by WuXi Xpress...

Research Field Biomedical engineering

Fiber Fantastic

07/12/2019 | Jonathan James

Sitting Down with Michael Tanner, Research Fellow in the School of Engineering and Physical Sciences at Heriot Watt University, Edinburgh, UK.

Research Field Biomedical engineering

Corneal Construction

07/05/2019 | Jonathan James

Researchers fine-tune 3D printing technology to create better biomimetic corneas – and predict a “breakthrough” in global transplantation practice.

Tools & Techniques Omics

A Microbial Map to Cancer

07/05/2019 | Michael Schubert

A new study uses machine learning to perform meta-analysis of eight metagenomic studies linking gut microbial signatures with colorectal cancer.

Disease Area Metabolism & Diabetes

Tackling the Fatty-Liver Timebomb

06/28/2019 | Jonathan James

Could modulation of fibroblast growth factor 21 translate into a new treatment for non-alcoholic fatty liver disease?

Research Field Microbiology

Breaking Down Walls

06/25/2019 | Danny Ward

To truly understand the intricacies of pathogenic bacteria, we need to combine “pure” and translational research.

Disease Area Metabolism & Diabetes

IEM Identification

06/21/2019 | Jonathan James

Combining metabolomics and DNA sequencing could be the key to discovering new inborn errors of metabolism in children.

Tools & Techniques Imaging

Revamping the Digital Interface

06/20/2019 | Luke Turner

We sit down with digital pathology advocate David Wilbur to discuss how the advancement of digital interfaces could lead to widespread adoption.

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Latest Solutions

High precision and reproducible kinetic characterization and custom quantitation

10/07/2019 | Contributed by ForteBio

Integrated workflow for rapid selection and optimization of hybridoma cell lines

09/10/2019 | Contributed by ForteBio

Tools & Techniques Analytical science

A Fast and High Precision Influenza Vaccine Potency Assay

07/09/2019 | Contributed by ForteBio

Tools & Techniques Analytical science

Top reasons to upgrade to a Q Exactive HF-X hybrid quadrupole-Orbitrap mass spectrometer

03/23/2018 | Contributed by Thermo Fisher Scientific

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Webinars on Demand

Tools & Techniques

Consistency, consistency - Automated Sample Prep for Translational Proteomics

03/17/2020 | Sponsored by Thermo Fisher Scientific

High-throughput LC-MS workflows are essential in translational and clinical research proteomics.

Tools & Techniques Clinical trials

Multimodal molecular spectroscopy for medical diagnosis and therapy

04/09/2019 | Sponsored by Andor

The webinar will look at efforts to translate researched multimodal spectroscopic approaches into automated systems with a high technology readiness level (TRL) for clinical applications.

Disease Area Omics

Monitoring Kinome Adaptations to Therapy using Quantitative High Resolution Mass Spectrometry

05/26/2016 | Sponsored by Thermo Fisher Scientific

Learn how studying the kinome as a whole entity, can aide in understanding how tumors may evade current therapies by altering their kinome state.

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Most popular articles

1. Disease Area Outcomes research

Efficacy vs Effectiveness

09/28/2016 | William Aryitey

Tightly controlled efficacy studies can’t predict real-word effectiveness

2. Research Field Cancer

No Biomarker, No Trial?

03/02/2016 | James Ritchie, Sidath Katugampola, Paul Jones

The vast majority of experimental cancer drugs fail during the later stages of clinical development

3. Research Field Clinical trials

From Acne to MS

06/27/2017 | Roisin McGuigan

A recent clinical trial finds a new use for an old antibiotic.

4. Research Field Cell & molecular biology

In the RNA

07/12/2019 | Stephanie Sutton

RNA Inhibitors - an exciting avenue for drug development? We collate the findings from the Innovation that Matters series, hosted by WuXi Xpress...

5. Tools & Techniques Drug delivery

The Overactive Brain

01/21/2016 | Michela Gallagher

Michela Gallagher was studying aging in lab rats when an unusual finding launched her on a translational journey that now sees her poised to initiate a Phase III trial of a drug to delay the onset of Alzheimer’s dementia.

Disease Area

Neurological