Disease Area Neurological

Getting on Target for Alzheimer’s

01/03/2020 | Neil Cashman, James Kupiec

Biogen’s aducanumab reversal not only puts hope on the horizon for a near-term Alzheimer’s treatment, it also revitalizes work supporting next-generation amyloid beta (Aß)-targeting candidates.

Tools & Techniques Clinical trials

A Framework for Translation

12/09/2019 | Jonathan James

Andrew Davies, Professor of Haematological Oncology and Consultant Medical Oncologist at the University of Southampton, and Nigel Blackburn, Cancer Research UK’s Director of Drug Development, discuss a partnership that focuses on early-phase clinical trials

Research Field Neuroscience

A Better AD Model

07/29/2019 | Brett Spangler

How primary neuronal cell cultures are unraveling the role of amyloid β oligomers in Alzheimer’s disease.

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Latest Articles

Tools & Techniques Diagnostics & prognostics

All the RAGE

09/24/2019 | Luke Turner

A new genomic barcode tracker could help spot the rare immune cells that are most effective against cancer

Research Field Pain & critical care

An Osteoarthritic Odyssey

07/23/2019

Sitting Down With… Mike Clayman, CEO of Flexion Therapeutics, Inc., Burlington, Massachusetts, USA.

Research Field Cell & molecular biology

In the RNA

07/12/2019 | Stephanie Sutton

RNA Inhibitors - an exciting avenue for drug development? We collate the findings from the Innovation that Matters series, hosted by WuXi Xpress...

Research Field Biomedical engineering

Fiber Fantastic

07/12/2019 | Jonathan James

Sitting Down with Michael Tanner, Research Fellow in the School of Engineering and Physical Sciences at Heriot Watt University, Edinburgh, UK.

Research Field Biomedical engineering

Corneal Construction

07/05/2019 | Jonathan James

Researchers fine-tune 3D printing technology to create better biomimetic corneas – and predict a “breakthrough” in global transplantation practice.

Tools & Techniques Omics

A Microbial Map to Cancer

07/05/2019 | Michael Schubert

A new study uses machine learning to perform meta-analysis of eight metagenomic studies linking gut microbial signatures with colorectal cancer.

Disease Area Metabolism & Diabetes

Tackling the Fatty-Liver Timebomb

06/28/2019 | Jonathan James

Could modulation of fibroblast growth factor 21 translate into a new treatment for non-alcoholic fatty liver disease?

Research Field Microbiology

Breaking Down Walls

06/25/2019 | Danny Ward

To truly understand the intricacies of pathogenic bacteria, we need to combine “pure” and translational research.

Disease Area Metabolism & Diabetes

IEM Identification

06/21/2019 | Jonathan James

Combining metabolomics and DNA sequencing could be the key to discovering new inborn errors of metabolism in children.

Tools & Techniques Imaging

Revamping the Digital Interface

06/20/2019 | Luke Turner

We sit down with digital pathology advocate David Wilbur to discuss how the advancement of digital interfaces could lead to widespread adoption.

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Latest Solutions

High precision and reproducible kinetic characterization and custom quantitation

10/07/2019 | Contributed by ForteBio

Integrated workflow for rapid selection and optimization of hybridoma cell lines

09/10/2019 | Contributed by ForteBio

Tools & Techniques Analytical science

A Fast and High Precision Influenza Vaccine Potency Assay

07/09/2019 | Contributed by ForteBio

Tools & Techniques Analytical science

Top reasons to upgrade to a Q Exactive HF-X hybrid quadrupole-Orbitrap mass spectrometer

03/23/2018 | Contributed by Thermo Fisher Scientific

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Webinars on Demand

Tools & Techniques

Consistency, consistency - Automated Sample Prep for Translational Proteomics

03/17/2020 | Sponsored by Thermo Fisher Scientific

High-throughput LC-MS workflows are essential in translational and clinical research proteomics.

Tools & Techniques Clinical trials

Multimodal molecular spectroscopy for medical diagnosis and therapy

04/09/2019 | Sponsored by Andor

The webinar will look at efforts to translate researched multimodal spectroscopic approaches into automated systems with a high technology readiness level (TRL) for clinical applications.

Disease Area Omics

Monitoring Kinome Adaptations to Therapy using Quantitative High Resolution Mass Spectrometry

05/26/2016 | Sponsored by Thermo Fisher Scientific

Learn how studying the kinome as a whole entity, can aide in understanding how tumors may evade current therapies by altering their kinome state.

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Most popular articles

1. Disease Area Outcomes research

Efficacy vs Effectiveness

09/28/2016 | William Aryitey

Tightly controlled efficacy studies can’t predict real-word effectiveness

2. Research Field Clinical trials

From Acne to MS

06/27/2017 | Roisin McGuigan

A recent clinical trial finds a new use for an old antibiotic.

3. Tools & Techniques Analytical science

The Hunt for an HD Blood Test

07/05/2017 | Roisin McGuigan

Do we finally have an effective blood biomarker for studying progression of Huntington’s disease?

4. Research Field Drug discovery

Arresting ALS

05/26/2016 | Joe Beckman

When it comes to prognosis, the mouse models I use to study amyotrophic lateral sclerosis (ALS) are sadly accurate – like their human counterparts with familial ALS, all mice with these mutations die young. After 20 years of trying – and failing – to find a treatment that could extend life, I was close to giving up, until a new drug candidate came along. Then something amazing happened – a mouse lived.

5. Research Field Clinical trials

Reuse, Recycle, Regenerate

05/10/2017 | Roisin McGuigan

Two repurposed drugs prevent neurodegeneration in mice – and both are already in clinical use.

Disease Area

Neurological