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Research Field Neuroscience

Decoding Depression

| Jonathan James

The publication of over 100 genetic markers associated with depression has rocked the neuroscience community. Here, we sit down with one of the authors to find out more.

Disease Area Neurological

Neurons Under (Astroctyic) Attack

| Jonathan James

Could manipulation of micro-RNA cross-talk between astrocytes and neuronal cells yield a new therapeutic avenue for ALS?

Tools & Techniques Diagnostics & prognostics

Getting to the Heart of the Matter

| Jonathan James

How a combinatorial approach to assessing coronary heart disease could improve diagnosis.

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Latest Articles

Tools & Techniques Diagnostics & prognostics

A Nose for Cancer

| Jonathan James

Could a multi-layer graphene (MLG)-based biomarker sensor offer the sensitivity needed for earlier lung cancer detection?

Disease Area Cancer

Two-pronged Attack on Neuroblastoma

| Jonathan James

How inhibiting both polyamine synthesis (with DFMO) and uptake (with new small molecule AMXT 1501) could delay tumor development.

Tools & Techniques Diagnostics & prognostics

Biomarkers Beyond Our Wildest Dreams

| Luke Turner

Different glycosylation patterns in patients with idiopathic REM sleep behavior disorder could predict the future onset of neurodegenerative disease.

Research Field Genetics

From Sports Captain to Genome Mapper

| Luke Turner

We sit down with England’s Chief Scientific Officer, Professor Dame Sue Hill, to learn how genomics will influence the future of pathology.

Tools & Techniques Drug delivery

Heavy Metal Wonder

| Jonathan James

An iridium-based photodynamic drug accumulates in cancer cell nuclei – and destroys them from within.

Research Field Cell & gene therapy

Perusing the Pipeline

| James Strachan

With cell and gene therapies being all the rage, we take a peek at some of the advanced therapies coming down the pipe.

Research Field Microbiology

Monitoring the Microbiome

| Luke Turner

Differences in bacterial diversity in the gut could be used to identify patients with Barrett’s esophagus and esophageal cancer.

Research Field Cell & gene therapy

Swimming against the nucleotides

| James Bainbridge

Tomorrow’s cures for retinopathies will likely include advanced gene and cell therapies delivered by precision surgery.

Research Field Gene Editing

It's CRISPR Crunch Time

| Jonathan James

China drafts new gene-editing regulations – but concerns over their enforcement remain.

Tools & Techniques Cancer

The Story and Science Behind the "Mini-brain"

| Simon Plummer

How iPSC-derived 3D organoids and high-throughput histology opens a new door to personalized medicine development and testing.

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